Hearing that your dog has cancer can feel overwhelming. At CTAC, we understand the difficult emotions that come with this diagnosis, and we’re here to help you explore every option available. If a Bone Marrow Transplant (BMT) is something you’re considering, it’s important to contact our team as soon as possible.
We will work closely with your veterinarian to ensure your dog is properly prepared for BMT. This may include adjustments to their current cancer treatment plan to align with the transplant protocol. Our goal is to provide a seamless, supportive experience as you navigate this challenging journey with your beloved companion.
After reaching out to CTAC, you will have an initial consultation with our oncologist, who will guide you through every step of the process.
Following this consultation, you and the oncologist will decide together whether pursuing the transplant is the best path for your dog.
For an autologous BMT, your dog will need to receive high dose cyclophosphamide (chemotherapy) at your local oncologist to help eliminate all cancer cells from the blood, since the stem cells will be collected from their blood two weeks later. This step is not needed for an allogeneic BMT, since the matched donor dog does not have lymphoma.
Your dog will undergo a comprehensive evaluation to ensure they are healthy enough for the procedure. This includes:
These tests can be performed locally or at CTAC upon arrival.
At the time of your dog’s admission, you and your family will participate in an informed consent conference with the oncologist.
This is an important opportunity to ensure you fully understand every aspect of the transplant process and have all your questions answered.
If your dog is receiving an autologous BMT, they will need to arrive at CTAC five days before cell collection. For allogeneic transplants, both your dog and the matched donor will be admitted, with the donor typically able to return home the following day after cell collection.
Immediately following TBI, the harvested stem cells will be infused via an IV catheter by our medical oncologist. This is the last step in the BMT protocol.
Once the previously collected stem cells are infused, they travel to the bone marrow and begin the process of engraftment.
To prioritize your pet’s safety, visits can be discussed, but access will be restricted for the first week or so before becoming less limited. If in person visits are determined to be too high of a risk, we can facilitate virtual visits for you to check up on your pet. You can feel confident knowing your dog is being carefully monitored and lovingly cared for.
Once your dog is cleared to go home, they will still require rest to support their full recovery. Follow-up care includes regular blood work rechecks with your primary veterinarian to monitor progress and ensure a smooth recovery. Our team will provide detailed instructions to help your dog transition safely back to their home environment.
At CTAC, we’re committed to providing the highest level of care and support for both you and your dog throughout the BMT process. If you’re ready to take the next step or simply want to learn more about how we can help, our team is here to answer your questions and guide you every step of the way.
We understand that patients and their families may have many questions regarding our services, policies, and procedures.
BMTs are primarily used to treat blood cell cancers and diseases that affect the bone marrow. At CTAC we mainly use BMT to treat dogs with high-grade B- and T-cell lymphomas. We also may be able to treat dogs with acute leukemias if a matched donor dog can be located quickly. If you're wondering whether BMT is a suitable treatment option for your dog, please reach out to us for a consultation.
Your dog’s eligibility depends on factors such as overall health and type of disease. A consultation with our oncology team is necessary to determine suitability.
Yes, BMT's are available for dogs of all breeds as long as they meet the necessary health criteria. Dogs as small as 5 kg can also be eligible.
The best donor is typically a closely related dog, such as a littermate or parent. Our team will guide you through what this means for your dog and discuss the chances of finding a suitable donor during consultation.
We provide a comprehensive BMT Handbook to all pet owners inquiring about additional information regarding the transplant process. This handbook includes detailed guidelines, expectations, and resources to help you make an informed decision.
Your dog’s stay typically ranges from 2.5 to 4 weeks, including time for monitoring and recovery.
Our patients receive individualized care from a dedicated team experienced in bone marrow transplantation. In addition to medical treatment and monitoring, we focus on each dog's comfort and emotional well-being throughout their stay.
Dogs receive daily nursing care, enrichment, exercise as appropriate, and plenty of one-on-one attention. Our team gets to know each patient's personality, preferences, and routines so we can provide care that feels as familiar and comforting as possible.
We also keep pet parents informed with regular updates and communication throughout the transplant process.
Following total body irradiation and stem cell transplantation, your dog's white blood cell count will temporarily drop to very low levels. During this time, their immune system is less able to fight infection, making them more vulnerable to bacteria and other pathogens.
To help protect them, patients stay in a specialized isolation environment until their blood counts recover to a safe level. While visitation is temporarily restricted during this phase, our team provides around-the-clock nursing care, enrichment, comfort, and daily updates to keep both patients and families connected throughout the process.
Changes in appetite are common during the bone marrow transplant process. Some dogs may eat less than usual for a period of time, while others become more selective about what they want to eat.
Our team closely monitors each patient's nutritional intake and works to find foods that are both appealing and appropriate for their individual needs. We offer a variety of feeding options, accommodate dietary sensitivities whenever possible, and tailor feeding plans based on each patient's needs.
When extra encouragement is needed, our nurses often spend additional one-on-one time with patients, including hand feeding and finding creative ways to encourage eating. We know that maintaining nutrition is an important part of recovery, and we meet each patient where they are.
Proper nutrition plays an important role in healing, and we are committed to supporting each patient through every stage of the transplant process.
Yes, visits are permitted. However, there will be a critical period during isolation when we recommend minimizing contact to reduce the risk of infection. We will provide daily updates during this time.
Yes, we work closely with referring veterinarians to ensure comprehensive care. A referral from your veterinarian, along with your dog’s medical history, will be needed to help us assess your dog’s eligibility. You are also welcome to reach out to us directly.
To schedule a consultation, please contact us through our contact portal or have your veterinarian submit a referral.
Some owners choose to stay nearby while their dog undergoes treatment as Chattanooga, TN, offers many convenient lodging options. Others may return home and only come back for their dog’s discharge.
After the procedure, your dog will require regular follow-up visits with your referring veterinarian, medication management, and close monitoring. We will provide a detailed aftercare plan tailored to your dog’s specific needs.
Outcomes vary by case, but studies have shown promising results. For autologous BMTs (using the dog’s own stem cells), the cure rate (defined as living over 2 years post-transplant) is ~33-40% for dogs with high-grade B-cell lymphoma and ~19% for those with high-grade T-cell lymphoma. For allogeneic BMTs (using donor stem cells), the cure rate for high-grade B-cell lymphoma is ~89% based on early studies. We will discuss what these results mean for your dog during the consultation.
Our dedicated care team, including full-time nurses and doctors, is here to support you and answer any questions you may have.