Hearing that your dog has cancer can feel overwhelming. At CTAC, we understand the difficult emotions that come with this diagnosis, and we’re here to help you explore every option available. If a Hematopoietic Stem Cell Transplant (HSCT) is something you’re considering, it’s important to contact our team as soon as possible.
We will work closely with your veterinarian to ensure your dog is properly prepared for HSCT. This may include adjustments to their current cancer treatment plan to align with the transplant protocol. Our goal is to provide a seamless, supportive experience as you navigate this challenging journey with your beloved companion.
After reaching out to CTAC, you will have an initial consultation with our oncologist, who will guide you through every step of the process. If a donor is needed, we’ll discuss the potential options.
Following this consultation, you and the oncologist will decide together whether pursuing the transplant is the best path for your dog.
Before beginning the HSCT process, your dog will need a high dose of cyclophosphamide (chemotherapy) to help eliminate as many cancer cells as possible and to prepare its body before stem cell collection. This treatment is typically administered about two weeks prior to admission at CTAC and can be coordinated through your local oncologist.
Your dog will undergo a comprehensive evaluation to ensure they are healthy enough for the procedure. This includes:
These tests can be performed locally or at CTAC upon arrival.
At the time of your dog’s admission, you and your family will participate in an informed consent conference with the oncologist.
This is an important opportunity to ensure you fully understand every aspect of the transplant process and have all your questions answered.
If your dog is receiving an autologous transplant, they will need to arrive at CTAC five days before stem cell collection. For allogeneic transplants, both your dog and the matched donor will be admitted, with the donor typically able to return home the same day or the following day after stem cell collection.
Immediately following radiation therapy, the harvested stem cells are transplanted through an IV catheter by our radiation oncologist, with the goal of killing all the cancer cells in your dogs body (autologous) or making space for the donor cells (allogeneic).
Within hours of the transplant, the newly transplanted stem cells will travel to the bone marrow and begin the process of engraftment.
To prioritize your pet’s safety, visits can be discussed, but access will be restricted for the first week or so before becoming less limited. If in person visits are determined to be too high of a risk, we can facilitate virtual visits for you to check up on your pet. You can feel confident knowing they are being carefully monitored and lovingly cared for.
Once your dog is cleared to go home, they will still require rest to support their full recovery. Follow-up care includes regular blood work rechecks with your primary veterinarian to monitor progress and ensure a smooth recovery. Our team will provide detailed instructions to help your dog transition safely back to their home environment.
At CTAC, we’re committed to providing the highest level of care and support for both you and your dog throughout the HSCT process. If you’re ready to take the next step or simply want to learn more about how we can help, our team is here to answer your questions and guide you every step of the way.
We understand that patients and their families may have many questions regarding our services, policies, and procedures.
HSCTs are primarily used to treat blood cancers like lymphoma, leukemia, and other hematologic (blood-related) cancers or disorders. If you’re wondering whether HSCT is a suitable option for your dog, please reach out to us for a consultation.
Your dog’s eligibility depends on factors such as overall health, type of disease, ability to find a donor and prior treatment history. A consultation with our oncology team is necessary to determine suitability.
Yes, we work closely with referring veterinarians to ensure comprehensive care. A referral from your veterinarian, along with your dog’s medical history, will help us assess your dog’s eligibility.
Yes, HSCTs are available for dogs of all breeds as long as they meet the necessary health criteria. Dogs as small as 5 kg can also be eligible.
Your dog’s stay typically ranges from 2.5 to 4 weeks, including time for monitoring and recovery.
The best donor is a genetically matched littermate or parent. A match increases the success rate of the transplant. There is a 25% chance that any brother or sister will have the same genes as the patient. For a biological parent, there’s a 50% chance of being partially matched. During consultation, our team will discuss the likelihood of finding a suitable donor for your dog.
We provide a comprehensive HSCT Handbook to all pet owners inquiring about additional information regarding the transplant process. This handbook includes detailed guidelines, expectations, and resources to help you make an informed decision.
Costs vary depending on the complexity of the case. We will provide a detailed estimate during the consultation. Payment plans and financing options may be available.
To schedule a consultation, please contact us through our contact portal or have your veterinarian submit a referral.
After the procedure, your dog will require regular follow-up visits with your referring veterinarian, medication management, and close monitoring. We will provide a detailed aftercare plan tailored to your dog’s specific needs.
Outcomes vary by case, but studies have shown promising results. For autologous HSCTs (using the dog’s own stem cells), the cure rate (defined as living over 2 years post-transplant) is ~33% for dogs with B-cell lymphoma and ~19% for those with T-cell lymphoma. For allogeneic BMTs (using donor stem cells), the cure rate for high-grade B-cell lymphoma is ~89% based on early studies. We will discuss what these results mean for your dog during the consultation.
Our dedicated care team, including full-time nurses and doctors, is here to support you and answer any questions you may have.
Yes, visits are permitted. However, there will be a critical period during isolation when we recommend minimizing contact to reduce the risk of infection. We will provide daily updates during this time.
Some owners choose to stay nearby while their dog undergoes treatment as Chattanooga, TN, offers many convenient lodging options. Others may return home and only come back for their dog’s discharge.